diff --git a/build/fbcode_builder/getdeps/builder.py b/build/fbcode_builder/getdeps/builder.py
index 0b5e7d2ce..733426605 100644
--- a/build/fbcode_builder/getdeps/builder.py
+++ b/build/fbcode_builder/getdeps/builder.py
@@ -271,9 +271,13 @@ class CMakeBuilder(BuilderBase):
             "CMAKE_BUILD_TYPE": "RelWithDebInfo",
         }
         env = self._compute_env(install_dirs)
-        ccache = path_search(env, "ccache")
-        if ccache:
-            defines["CMAKE_CXX_COMPILER_LAUNCHER"] = ccache
+        if "SANDCASTLE" not in os.environ:
+            # We sometimes see intermittent ccache related breakages on some
+            # of the FB internal CI hosts, so we prefer to disable ccache
+            # when running in that environment.
+            ccache = path_search(env, "ccache")
+            if ccache:
+                defines["CMAKE_CXX_COMPILER_LAUNCHER"] = ccache
         if self.build_opts.is_darwin():
             # Try to persuade cmake to set the rpath to match the lib
             # dirs of the dependencies.  This isn't automatic, and to