diff --git a/tests/scripts/depends.py b/tests/scripts/depends.py
index 0c77e67291..2c38f9d705 100755
--- a/tests/scripts/depends.py
+++ b/tests/scripts/depends.py
@@ -263,7 +263,20 @@ REVERSE_DEPENDENCIES = {
 # if a given define is the only one enabled from an exclusive group.
 EXCLUSIVE_GROUPS = {
     'MBEDTLS_SHA512_C': ['-MBEDTLS_SSL_PROTO_TLS1_3_EXPERIMENTAL'],
-    'MBEDTLS_SHA512_NO_SHA384': ['+MBEDTLS_SHA512_C'],
+    'MBEDTLS_SHA512_NO_SHA384': ['+MBEDTLS_SHA512_C',
+                                 '-MBEDTLS_SSL_PROTO_TLS1_2',
+                                 '-MBEDTLS_SSL_PROTO_DTLS',
+                                 '-MBEDTLS_SSL_TLS_C',
+                                 '-MBEDTLS_SSL_CLI_C',
+                                 '-MBEDTLS_SSL_SRV_C',
+                                 '-MBEDTLS_SSL_DTLS_HELLO_VERIFY',
+                                 '-MBEDTLS_SSL_DTLS_ANTI_REPLAY',
+                                 '-MBEDTLS_SSL_DTLS_CONNECTION_ID',
+                                 '-MBEDTLS_SSL_DTLS_BADMAC_LIMIT',
+                                 '-MBEDTLS_SSL_ENCRYPT_THEN_MAC',
+                                 '-MBEDTLS_SSL_EXTENDED_MASTER_SECRET',
+                                 '-MBEDTLS_SSL_DTLS_SRTP',
+                                 '-MBEDTLS_SSL_DTLS_CLIENT_PORT_REUSE'],
     'MBEDTLS_ECP_DP_CURVE448_ENABLED': ['-MBEDTLS_ECDSA_C',
                                         '-MBEDTLS_ECDSA_DETERMINISTIC',
                                         '-MBEDTLS_KEY_EXCHANGE_ECDHE_ECDSA_ENABLED',