diff --git a/include/mbedtls/mbedtls_config.h b/include/mbedtls/mbedtls_config.h
index 0f1b54e226..a256c36211 100644
--- a/include/mbedtls/mbedtls_config.h
+++ b/include/mbedtls/mbedtls_config.h
@@ -387,7 +387,6 @@
  *            implementation should be provided for mbedtls_ecdsa_sign_det_ext().
  *
  */
-//#define MBEDTLS_MD5_PROCESS_ALT
 //#define MBEDTLS_RIPEMD160_PROCESS_ALT
 //#define MBEDTLS_SHA1_PROCESS_ALT
 //#define MBEDTLS_SHA256_PROCESS_ALT
diff --git a/tf-psa-crypto/drivers/builtin/src/md5.c b/tf-psa-crypto/drivers/builtin/src/md5.c
index e11e078095..98b8ee4e9c 100644
--- a/tf-psa-crypto/drivers/builtin/src/md5.c
+++ b/tf-psa-crypto/drivers/builtin/src/md5.c
@@ -58,7 +58,6 @@ int mbedtls_md5_starts(mbedtls_md5_context *ctx)
     return 0;
 }
 
-#if !defined(MBEDTLS_MD5_PROCESS_ALT)
 int mbedtls_internal_md5_process(mbedtls_md5_context *ctx,
                                  const unsigned char data[64])
 {
@@ -193,8 +192,6 @@ int mbedtls_internal_md5_process(mbedtls_md5_context *ctx,
     return 0;
 }
 
-#endif /* !MBEDTLS_MD5_PROCESS_ALT */
-
 /*
  * MD5 process buffer
  */