diff --git a/tests/include/test/psa_crypto_helpers.h b/tests/include/test/psa_crypto_helpers.h
index 55f24e0f89..18d46d8b2b 100644
--- a/tests/include/test/psa_crypto_helpers.h
+++ b/tests/include/test/psa_crypto_helpers.h
@@ -21,7 +21,8 @@
 #include "mbedtls/psa_util.h"
 #endif
 
-#if defined(MBEDTLS_TEST_HOOKS) && defined(MBEDTLS_PSA_CRYPTO_C)
+#if defined(MBEDTLS_TEST_HOOKS) && defined(MBEDTLS_PSA_CRYPTO_C) \
+    && defined(MBEDTLS_PSA_COPY_CALLER_BUFFERS)
 #include "test/psa_memory_poisoning_wrappers.h"
 #endif
 
diff --git a/tests/src/helpers.c b/tests/src/helpers.c
index 27a7a7a152..fd7b548d11 100644
--- a/tests/src/helpers.c
+++ b/tests/src/helpers.c
@@ -51,6 +51,7 @@ int mbedtls_test_platform_setup(void)
     int ret = 0;
 
 #if defined(MBEDTLS_TEST_HOOKS) && defined(MBEDTLS_PSA_CRYPTO_C) \
+    && defined(MBEDTLS_PSA_COPY_CALLER_BUFFERS) \
     && defined(MBEDTLS_TEST_MEMORY_CAN_POISON)
     mbedtls_poison_test_hooks_setup();
 #endif
@@ -76,6 +77,7 @@ int mbedtls_test_platform_setup(void)
 void mbedtls_test_platform_teardown(void)
 {
 #if defined(MBEDTLS_TEST_HOOKS) && defined(MBEDTLS_PSA_CRYPTO_C) \
+    && defined(MBEDTLS_PSA_COPY_CALLER_BUFFERS) \
     &&  defined(MBEDTLS_TEST_MEMORY_CAN_POISON)
     mbedtls_poison_test_hooks_teardown();
 #endif