diff --git a/mysql-test/include/not_valgrind_build.inc b/mysql-test/include/not_valgrind_build.inc
new file mode 100644
index 00000000000..b62a1bc953b
--- /dev/null
+++ b/mysql-test/include/not_valgrind_build.inc
@@ -0,0 +1,4 @@
+if (`select version() like '%valgrind%' || version() like '%asan%'`)
+{
+  skip Does not run with binaries built with valgrind or asan;
+}
diff --git a/mysql-test/main/sp-no-valgrind.test b/mysql-test/main/sp-no-valgrind.test
index 1b4a0f84f1e..6bacc7b150c 100644
--- a/mysql-test/main/sp-no-valgrind.test
+++ b/mysql-test/main/sp-no-valgrind.test
@@ -1,5 +1,5 @@
 --source include/not_msan.inc
---source include/not_valgrind.inc
+--source include/not_valgrind_build.inc
 
 --echo # MDEV-20699 do not cache SP in SHOW CREATE
 --echo # Warmup round, this might allocate some memory for session variable