diff --git a/mysql-test/r/selectivity.result b/mysql-test/r/selectivity.result
index dc7e9494946..9bb197ad056 100644
--- a/mysql-test/r/selectivity.result
+++ b/mysql-test/r/selectivity.result
@@ -1866,4 +1866,19 @@ id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
 set optimizer_switch= @save_optimizer_switch;
 set optimizer_use_condition_selectivity= @save_optimizer_use_condition_selectivity;
 drop table t1,t2;
+#
+# MDEV-21495: Conditional jump or move depends on uninitialised value in sel_arg_range_seq_next
+#
+CREATE TABLE t1(a INT, b INT);
+INSERT INTO t1 SELECT seq, seq from seq_1_to_100;
+set optimizer_use_condition_selectivity=4;
+ANALYZE TABLE t1 PERSISTENT FOR ALL;
+Table	Op	Msg_type	Msg_text
+test.t1	analyze	status	Engine-independent statistics collected
+test.t1	analyze	status	OK
+SELECT * from t1 WHERE a = 5 and b = 5;
+a	b
+5	5
+set optimizer_use_condition_selectivity= @save_optimizer_use_condition_selectivity;
+drop table t1;
 # End of 10.1 tests
diff --git a/mysql-test/r/selectivity_innodb.result b/mysql-test/r/selectivity_innodb.result
index f0cbf1662aa..d0e31374784 100644
--- a/mysql-test/r/selectivity_innodb.result
+++ b/mysql-test/r/selectivity_innodb.result
@@ -1876,6 +1876,21 @@ id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
 set optimizer_switch= @save_optimizer_switch;
 set optimizer_use_condition_selectivity= @save_optimizer_use_condition_selectivity;
 drop table t1,t2;
+#
+# MDEV-21495: Conditional jump or move depends on uninitialised value in sel_arg_range_seq_next
+#
+CREATE TABLE t1(a INT, b INT);
+INSERT INTO t1 SELECT seq, seq from seq_1_to_100;
+set optimizer_use_condition_selectivity=4;
+ANALYZE TABLE t1 PERSISTENT FOR ALL;
+Table	Op	Msg_type	Msg_text
+test.t1	analyze	status	Engine-independent statistics collected
+test.t1	analyze	status	OK
+SELECT * from t1 WHERE a = 5 and b = 5;
+a	b
+5	5
+set optimizer_use_condition_selectivity= @save_optimizer_use_condition_selectivity;
+drop table t1;
 # End of 10.1 tests
 set optimizer_switch=@save_optimizer_switch_for_selectivity_test;
 set @tmp_ust= @@use_stat_tables;
diff --git a/mysql-test/t/selectivity.test b/mysql-test/t/selectivity.test
index 7df326edb44..1d0256b1b7e 100644
--- a/mysql-test/t/selectivity.test
+++ b/mysql-test/t/selectivity.test
@@ -1266,5 +1266,17 @@ set optimizer_switch= @save_optimizer_switch;
 set optimizer_use_condition_selectivity= @save_optimizer_use_condition_selectivity;
 drop table t1,t2;
 
+--echo #
+--echo # MDEV-21495: Conditional jump or move depends on uninitialised value in sel_arg_range_seq_next
+--echo #
+
+CREATE TABLE t1(a INT, b INT);
+INSERT INTO t1 SELECT seq, seq from seq_1_to_100;
+set optimizer_use_condition_selectivity=4;
+ANALYZE TABLE t1 PERSISTENT FOR ALL;
+SELECT * from t1 WHERE a = 5 and b = 5;
+set optimizer_use_condition_selectivity= @save_optimizer_use_condition_selectivity;
+drop table t1;
+
 --echo # End of 10.1 tests
 
diff --git a/sql/opt_range_mrr.cc b/sql/opt_range_mrr.cc
index 5d62ceda7d4..b1894f4b6c4 100644
--- a/sql/opt_range_mrr.cc
+++ b/sql/opt_range_mrr.cc
@@ -73,6 +73,7 @@ range_seq_t sel_arg_range_seq_init(void *init_param, uint n_ranges, uint flags)
 {
   SEL_ARG_RANGE_SEQ *seq= (SEL_ARG_RANGE_SEQ*)init_param;
   seq->at_start= TRUE;
+  seq->param->max_key_part= 0;
   seq->stack[0].key_tree= NULL;
   seq->stack[0].min_key= seq->param->min_key;
   seq->stack[0].min_key_flag= 0;