diff --git a/mysql-test/include/mtr_warnings.sql b/mysql-test/include/mtr_warnings.sql
index b9a2b2addb3..462a900df6d 100644
--- a/mysql-test/include/mtr_warnings.sql
+++ b/mysql-test/include/mtr_warnings.sql
@@ -201,6 +201,12 @@ INSERT INTO global_suppressions VALUES
  ("==[0-9]*== For more details"),
  /* This comes with innodb plugin tests */
  ("==[0-9]*== Warning: set address range perms: large range"),
+
+ /* valgrind warnings: invalid file descriptor -1 in syscall
+    write()/read(). Bug #50414 */
+ ("==[0-9]*== Warning: invalid file descriptor -1 in syscall write()"),
+ ("==[0-9]*== Warning: invalid file descriptor -1 in syscall read()"),
+
  /*
    Transient network failures that cause warnings on reconnect.
    BUG#47743 and BUG#47983.